DislikedAnswer can depend on your trading time frame but what i used to recommand when i was managing trading seminars years ago and this question was always askedwas :
Once you have a decent profit exit half of your position in profit and put a stop at BE+1pip ( just to get a profit on that remaining position in case you are stopped)
If you get stoped you still have a winner , if not you can make a lot of pips and more important you are confortable following the position because you know that whatever happens you have a winner.
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